The increased PTH in addition to makes the fresh new renal to increase hormonal regarding step 1,dos5(OH)

The increased PTH in addition to makes the fresh new renal to increase hormonal regarding step 1,dos5(OH)

Serum calcium homeostasis has evolved to simultaneously maintain extracellular ionized calcium levels in the physiologic range while allowing the flow of calcium to and from essential stores. A decrease in serum calcium inactivates the CaR in the parathyroid glands to increase PTH secretion, which acts on the PTHR in kidney to increase tubular calcium reabsorption, and in bone to increase net bone resorption. 2D, which activates the VDR in gut to increase calcium absorption, in the parathyroid glands to decrease PTH secretion, and in bone to increase resorption. The decrease in serum calcium probably also inactivates the CaR in kidney to increase calcium reabsorption and potentiate the effect of PTH. “The increased PTH in addition to makes the fresh new renal to increase hormonal regarding step 1,dos5(OH)” の続きを読む